Bakuchiol
- Category
- Cosmetics and Personal Care
Origins:
Extracted from Psoralea corylifolia (Babchi), used in traditional Chinese and Indian medicine. Also found in Ulmus davidiana var. japonica. (Nizam et al., 2023; Krishna, Edachery and Athalathil, 2022; Lee et al., 2021; Mehra et al., 2024).
Key Features:
Anti-inflammatory, antioxidant, antimicrobial, anti-aging; improves skin conditions like hyperpigmentation (Nizam et al., 2023; Mehra et al., 2024; Lim et al., 2019; Lyons et al., 2020; Wang et al., 2020; Lu et al., 2025). Free radical scavenger, regulates collagen, inhibits EMT, effective against Staphylococcus aureus (Mehra et al., 2024; Lu et al., 2025; Lee et al., 2021; Lim et al., 2019; Tripathi et al., 2024).
Sustainability:
Naturally sourced; sustainable harvesting practices are important.
bio:drive - intelligent microbe design
Here’s what bio:drive says about Bakuchiol:
- Viable pathways recommended / (generated) 8
- Median pathway length 5 biochemical reactions
- Max free energy change 321 KJ.mol-1
- Max theoretical yield 32 %
- Predicted pathway bottlenecks 2 out of 8 reactions
- Enzyme variants recommended / (generated) 2,000
- Predicted enzyme reactivity improvement 200x
- Predicted host microbe bottlenecks 8 genetic edits
- Predicted host microbe flux improvement 200x
- Continuous fermentation enabled
- Number of microbe versions designed for grow:bot build >10,000,000
- Overall potential improvement with bio:drive 20,000-40,000x
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