Ambrein

bio:drive - intelligent microbe design

Here’s what bio:drive says about Ambrein:

• Viable pathways recommended / (generated) i
  ×

  Using our retrosynthesis algorithms, the number of viable biochemical routes generated and recommended to the target ingredient.

• Median pathway length biochemical reactions i
  ×

  Of the viable pathways recommended, the median number of biochemical reactions.

• Max free energy change KJ.mol-1 i
  ×

  For the most efficient pathway, the Gibbs free energy change.

• Max theoretical yield % i
  ×

  For the most efficient pathway, the maximum possible conversion of feedstock to the target ingredient based on reaction efficiency.

• Predicted pathway bottlenecks reactions i
  ×

  For the most efficient pathway, the number of biochemical reactions predicted to be limiting.

• Enzyme variants recommended / (generated) i
  ×

  For the pathway bottlenecks identified, the enzyme variants generated and recommended using our enzyme generation engine.

• Predicted enzyme reactivity improvement i
  ×

  With the enzyme variants recommended, the predicted improvement in performance.

• Predicted host microbe bottlenecks genetic edits i
  ×

  Number of recommended genetic edits to improve pathway flux to target ingredient.

• Predicted host microbe flux improvement i
  ×

  With the host microbe genetic edits, the predicted improvement in performance.

• Continuous fermentation i
  ×

  Whether strains can be built for industrial scale and continuous fermentation systems using our in-house stabilisation system.

• Number of microbe versions designed for grow:bot build i
  ×

  Diversity potential from pathway, enzyme and host microbe edits.

• Overall potential improvement with bio:drive i
  ×

  Potential improvement in yield vs. traditional methods.