Hyaluronic Acid

get this strain explore the tree of products
Category
Cosmetics and Personal Care
Build Complexity
Moderate / Difficult / Extreme

Origins:

Naturally occurring glycosaminoglycan in the human body and extracellular matrix (Iaconisi et al., 2023; Price, Berry and Navsaria, 2007; Gagneja, Capalash and Sharma, 2024).

Key Features:

Water retention, viscoelasticity, biocompatibility, wound healing, dermal filler; used in drug delivery (Yao et al., 2021; Brown and Jones, 2005; Iaconisi et al., 2023; Ding et al., 2022; Price, Berry and Navsaria, 2007; Gupta et al., 2019; Dosio et al., 2016). Maintains tissue hydration, involved in cellular processes and inflammatory response.

Sustainability:

Microbial fermentation reduces reliance on animal sources; marine-derived HA is another alternative (Abdel-Rahman and Abdel-Mohsen, 2023).

bio:drive - intelligent microbe design

Here’s what bio:drive says about Bakuchiol:

  • No of viable pathways identified 8
  • Median pathway length 5 biochemical reactions
  • Free energy change 321 KJ.mol-1
  • Best max theoretical yield 32%
  • Predicted pathway bottlenecks 2 out of 8 reactions
  • Detected enzyme variants 2000 (3.1m)
  • Predicted reactivity increases 200x
  • Host strain bottleneck predictions 8 genetic edits
  • Predicted flux improvement from optimisations 200x
  • Potential yield improvement 20,000-40,000x
  • Predicted diversity of strain combinations >10,000,000
  • Continuous fermentation enabled
  • Novelty
ready to build?

Ready to start building using grow:bot?

At twig, we find the best possible strain to produce your ingredients using our fast, automated builder, grow:bot. In a matter of weeks, you can go from concept to having your own engineered strain.

Our wet-lab combines fast micro-scale strain builds, with high-throughput fermentation screening. And all of our strains are built to last, ready for large-scale and continuous fermentation systems.

Other ingredients:

twig
Powered by  GDPR Cookie Compliance
Privacy Overview

This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.