
Dopamine
- Category
- Pharmaceuticals and Healthcare
Origins:
Monoamine compound, neurotransmitter in the brain, discovered in 1910, established as neurotransmitter by Arvid Carlsson. (Zhou, Chen and Yang, 2024).
Key Features:
Motor control, motivation, reward, cognitive functions; operates through G protein-coupled receptors; roles in plant growth and stress response. (Klein et al., 2018; Liu et al., 2020). Imbalances linked to neurological disorders (Parkinson’s, schizophrenia, ADHD).
Sustainability:
Sustainable production from renewable resources is a growing area of interest. (Zhou, Chen and Yang, 2024).
bio:drive - intelligent microbe design
Here’s what bio:drive says about Bakuchiol:
- Viable pathways recommended / (generated) 2 / (37)
- Median pathway length 2 biochemical reactions
- Max free energy change -65.4 KJ.mol-1
- Max theoretical yield 56.1 %
- Predicted pathway bottlenecks 3 reactions
- Enzyme variants recommended / (generated) 15 / (1705)
- Predicted enzyme reactivity improvement 4.2x
- Predicted host microbe bottlenecks 5 genetic edits
- Predicted host microbe flux improvement 14.5x
- Continuous fermentation enabled
- Number of microbe versions designed for grow:bot build 1,080,000
- Overall potential improvement with bio:drive 30x
Ready to start building using grow:bot?
At twig, we find the best possible microbe to produce your ingredients using our fast, automated builder, grow:bot. In a matter of weeks, you can go from concept to having your own engineered microbe.
Our wet-lab combines fast micro-scale microbe builds, with high-throughput fermentation screening. And all of our microbes are built to last, ready for large-scale and continuous fermentation systems.
