Dopamine

Dopamine

Category
Pharmaceuticals and Healthcare

Origins:

Monoamine compound, neurotransmitter in the brain, discovered in 1910, established as neurotransmitter by Arvid Carlsson. (Zhou, Chen and Yang, 2024).

Key Features:

Motor control, motivation, reward, cognitive functions; operates through G protein-coupled receptors; roles in plant growth and stress response. (Klein et al., 2018; Liu et al., 2020). Imbalances linked to neurological disorders (Parkinson’s, schizophrenia, ADHD).

Sustainability:

Sustainable production from renewable resources is a growing area of interest. (Zhou, Chen and Yang, 2024).

bio:drive - intelligent microbe design

Here’s what bio:drive says about Bakuchiol:

  • Viable pathways recommended / (generated) 2 / (37)
  • Median pathway length 2 biochemical reactions
  • Max free energy change -65.4 KJ.mol-1
  • Max theoretical yield 56.1 %
  • Predicted pathway bottlenecks 3 reactions
  • Enzyme variants recommended / (generated) 15 / (1705)
  • Predicted enzyme reactivity improvement 4.2x
  • Predicted host microbe bottlenecks 5 genetic edits
  • Predicted host microbe flux improvement 14.5x
  • Continuous fermentation enabled
  • Number of microbe versions designed for grow:bot build 1,080,000
  • Overall potential improvement with bio:drive 30x
ready to build?

Ready to start building using grow:bot?

At twig, we find the best possible microbe to produce your ingredients using our fast, automated builder, grow:bot. In a matter of weeks, you can go from concept to having your own engineered microbe.

Our wet-lab combines fast micro-scale microbe builds, with high-throughput fermentation screening. And all of our microbes are built to last, ready for large-scale and continuous fermentation systems.

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