Oleic Acid

Oleic Acid

Category
Cosmetics and Personal Care, Food and Agriculture

Origins:

Monounsaturated fatty acid in olive oil; key component of Mediterranean diet; synthesized endogenously by SCD1 (Santa-María et al., 2023; Piccinin et al., 2019).

Key Features:

Anti-inflammatory, antioxidant, improves insulin sensitivity, weight management (Santa-María et al., 2023; Palomer et al., 2017; Bowen et al., 2017).

Sustainability:

Traditional sourcing from olive and palm oil raises environmental concerns (Wang et al., 2022). Biotech approaches using oleaginous yeasts offer sustainable alternatives, reducing the need for extensive agricultural land (Wang et al., 2022; Pérez-Rodríguez et al., 2023).

bio:drive - intelligent microbe design

Here’s what bio:drive says about Oleic Acid:

  • Viable pathways recommended / (generated) 1 / (6,815)
  • Median pathway length 3 biochemical reactions
  • Max free energy change 33.3 KJ.mol-1
  • Max theoretical yield 23.5 %
  • Predicted pathway bottlenecks 2 reactions
  • Enzyme variants recommended / (generated) 10 / (1,129)
  • Predicted enzyme reactivity improvement 1.4x
  • Predicted host microbe bottlenecks 5 genetic edits
  • Predicted host microbe flux improvement 4.5x
  • Continuous fermentation enabled
  • Number of microbe versions designed for grow:bot build 216,000
  • Overall potential improvement with bio:drive 3x
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