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Adipic Acid

Adipic Acid

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Category
Industrial and Speciality Chemicals, Polymers and Plastics

Origins:

Key dicarboxylic acid for nylon-6,6, traditionally from petroleum; NOx emissions generated as a byproduct (Lesage et al., 2020; Wei et al., 2019; Sato, Aoki and Noyori, 1998).

Key Features:

Monomer for nylon-66 and polyurethane; used in plasticizers, lubricants, and food additives (Lin et al., 2019; Wei et al., 2019). Versatile industrial chemical; bio-based production is growing.

Sustainability:

Bio-based methods reduce nitrous oxide emissions; use of byproducts and recycling of catalysts enhance sustainability (Sato, Aoki and Noyori, 1998; Cronjé et al., 2023; Lesage et al., 2020).

bio:drive - intelligent microbe design

Here’s what bio:drive says about Adipic Acid:

  • Viable pathways recommended / (generated) 1 / (327)
  • Median pathway length 2 biochemical reactions
  • Max free energy change 24.3 KJ.mol-1
  • Max theoretical yield 92.3 %
  • Predicted pathway bottlenecks 2 reactions
  • Enzyme variants recommended / (generated) 10 / (10,000)
  • Predicted enzyme reactivity improvement 1.5x
  • Predicted host microbe bottlenecks 2 genetic edits
  • Predicted host microbe flux improvement 5x
  • Continuous fermentation enabled
  • Number of microbe versions designed for grow:bot build 7,200
  • Overall potential improvement with bio:drive 4x
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